The energy landscape of adenylate kinase during catalysis

The energy landscape of adenylate kinase during catalysis

Kinases perform phosphoryl-transfer reactions in milliseconds; without enzymes, these reactions would take about 8000 years under physiological conditions. Despite extensive studies, a comprehensive understanding of kinase energy landscapes, including both chemical and conformational steps, is lacki...

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Bibliographic Details
Main Authors: Kerns, S. Jordan, Agafonov, Roman V., Cho, Young-Jin, Pontiggia, Francesco, Otten, Renee, Pachov, Dimitar V., Kutter, Steffen, Phung, Lien A., Murphy, Padraig N., Thai, Vu, Alber, Tom, Hagan, Michael F., Kern, Dorothee
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318763/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318763/

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