Virtual Microfluidics for digital quantification and single-cell sequencing

Interest in highly parallelized analysis of single molecules and single cells is growing rapidly. Here we develop hydrogel-based virtual microfluidics as a simple alternative to complex engineered microfluidic systems for the compartmentalization of nucleic acid amplification reactions. We applied d...

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Bibliographic Details
Main Authors: Xu, Liyi, Brito, Ilana L., Alm, Eric J., Blainey, Paul C.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007149/