Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer

Transcriptional mechanisms epigenetically-regulated in tumoral tissues point out new targets for anti-cancer therapies. Carnitine palmitoyl transferase I (CPT1) is the rate-limiting enzyme in the transport of long-chain fatty acids for β-oxidation. Here we identified the tumor specific nuclear CPT1A...

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Bibliographic Details
Main Authors: Pucci, Sabina, Zonetti, Maria Josè, Fisco, Tommaso, Polidoro, Chiara, Bocchinfuso, Gianfranco, Palleschi, Antonio, Novelli, Giuseppe, Spagnoli, Luigi G., Mazzarelli, Paola
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991433/