Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet

There is growing evidence that mitochondrial dysfunction, and more specifically fatty acid β-oxidation impairment, is involved in the pathophysiology of non-alcoholic steatohepatitis (NASH). The goal of the present study was to achieve more understanding on the modification/s of carnitinepalmitoyltr...

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Bibliographic Details
Main Authors: Serviddio, Gaetano, Giudetti, Anna M., Bellanti, Francesco, Priore, Paola, Rollo, Tiziana, Tamborra, Rosanna, Siculella, Luisa, Vendemiale, Gianluigi, Altomare, Emanuele, Gnoni, Gabriele V.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164715/