Paternal chronic colitis causes epigenetic inheritance of susceptibility to colitis

Inflammatory bowel disease (IBD) arises by unknown environmental triggers in genetically susceptible individuals. Epigenetic regulation of gene expression may integrate internal and external influences and may thereby modulate disease susceptibility. Epigenetic modification may also affect the germ-...

Full description

Bibliographic Details
Main Authors: Tschurtschenthaler, Markus, Kachroo, Priyadarshini, Heinsen, Femke-Anouska, Adolph, Timon Erik, Rühlemann, Malte Christoph, Klughammer, Johanna, Offner, Felix Albert, Ammerpohl, Ole, Krueger, Felix, Smallwood, Sébastien, Szymczak, Silke, Kaser, Arthur, Franke, Andre
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990911/