Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data

Several pathogenic viruses such as hepatitis B and human immunodeficiency viruses may integrate into the host genome. These virus/host integrations are detectable using paired-end next generation sequencing. However, the low number of expected true virus integrations may be difficult to distinguish...

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Bibliographic Details
Main Authors: Forster, Michael, Szymczak, Silke, Ellinghaus, David, Hemmrich, Georg, Rühlemann, Malte, Kraemer, Lars, Mucha, Sören, Wienbrandt, Lars, Stanulla, Martin, Franke, Andre
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499804/