ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity

ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity

Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize properly to cell-cell junctions, suggesting that mislocalization of SCRIB contrib...

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Bibliographic Details
Main Authors:	Chen, Baoen, Zheng, Baohui, DeRan, Micael, Jarugumilli, Gopala K., Fu, Jianjun, Brooks, Yang S., Wu, Xu
Format:	Online
Language:	English
Published:	2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990496/

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