ZDHHC7-Mediated S-Palmitoylation of Scribble Regulates Cell Polarity
Scribble (SCRIB) is a tumor suppressor protein, playing critical roles in establishing and maintaining epithelial cell polarity. Paradoxically, SCRIB is frequently amplified in human cancers, however, fails to localize properly to cell-cell junctions, suggesting that mislocalization of SCRIB contrib...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990496/ |