Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

Mycobacterium tuberculosis synthesizes intra- and extracellular α-glucans that were believed to originate from separate pathways. The extracellular glucose polymer is the main constituent of the mycobacterial capsule that is thought to be involved in immune evasion and virulence. However, the role...

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Bibliographic Details
Main Authors: Koliwer-Brandl, Hendrik, Syson, Karl, van de Weerd, Robert, Chandra, Govind, Appelmelk, Ben, Alber, Marina, Ioerger, Thomas R., Jacobs, William R., Geurtsen, Jeroen, Bornemann, Stephen, Kalscheuer, Rainer
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981310/