Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis
•Nucleotide-glucose synthesis in Mycobacterium tuberculosis was analyzed.•The characterization of four enzymes involved in glucose-1P partitioning is reported.•Mycobacterial ADP-glucose pyrophosphorylase is allosterically regulated.•Trehalose-6P synthase exhibits higher catalytic efficiency for ADP-...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Elsevier Pub. Co
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331664/ |