Receptor tyrosine kinase (c-Kit) inhibitors: a potential therapeutic target in cancer cells

c-Kit, a receptor tyrosine kinase, is involved in intracellular signaling, and the mutated form of c-Kit plays a crucial role in occurrence of some cancers. The function of c-Kit has led to the concept that inhibiting c-Kit kinase activity can be a target for cancer therapy. The promising results of...

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Bibliographic Details
Main Authors: Abbaspour Babaei, Maryam, Kamalidehghan, Behnam, Saleem, Mohammad, Huri, Hasniza Zaman, Ahmadipour, Fatemeh
Format: Online
Language:English
Published: Dove Medical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975146/