Label-free optical quantification of structural alterations in Alzheimer’s disease

We present a wide-field quantitative label-free imaging of mouse brain tissue slices with sub-micrometre resolution, employing holographic microscopy and an automated scanning platform. From the measured light field images, scattering coefficients and anisotropies are quantitatively retrieved by usi...

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Bibliographic Details
Main Authors: Lee, Moosung, Lee, Eeksung, Jung, JaeHwang, Yu, Hyeonseung, Kim, Kyoohyun, Yoon, Jonghee, Lee, Shinhwa, Jeong, Yong, Park, YongKeun
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4971571/