Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Photo-transduction in cone segments (CS) is crucial for high acuity daytime vision. For ill-defined reasons, CS degenerate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which characterize geographic atrophy (GA). Our experiments confirm the loss of cone segme...

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Bibliographic Details
Main Authors: Eandi, Chiara M, Charles Messance, Hugo, Augustin, Sébastien, Dominguez, Elisa, Lavalette, Sophie, Forster, Valérie, Hu, Shulong Justin, Siquieros, Lourdes, Craft, Cheryl Mae, Sahel, José-Alain, Tadayoni, Ramin, Paques, Michel, Guillonneau, Xavier, Sennlaub, Florian
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969036/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969036/

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