Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

Physiologically, the retinal pigment epithelium (RPE) expresses immunosuppressive signals such as FAS ligand (FASL), which prevents the accumulation of leukocytes in the subretinal space. Age-related macular degeneration (AMD) is associated with a breakdown of the subretinal immunosuppressive enviro...

Full description

Bibliographic Details
Main Authors: Levy, Olivier, Calippe, Bertrand, Lavalette, Sophie, Hu, Shulong J, Raoul, William, Dominguez, Elisa, Housset, Michael, Paques, Michel, Sahel, José-Alain, Bemelmans, Alexis-Pierre, Combadiere, Christophe, Guillonneau, Xavier, Sennlaub, Florian
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328649/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4328649/

Similar Items