Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation

Maternal inflammation activated ROS-p38 MAPK predisposes offspring to heart damages caused by isoproterenol via augmenting ROS generation

Maternal inflammation contributes to the increased incidence of adult cardiovascular disease. The current study investigated the susceptibility of cardiac damage responding to isoproterenol (ISO) in adult offspring that underwent maternal inflammation (modeled by pregnant Sprague-Dawley rats with li...

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Bibliographic Details
Main Authors: Zhang, Qi, Deng, Yafei, Lai, Wenjing, Guan, Xiao, Sun, Xiongshan, Han, Qi, Wang, Fangjie, Pan, Xiaodong, Ji, Yan, Luo, Hongqin, Huang, Pei, Tang, Yuan, Gu, Liangqi, Dan, Guorong, Yu, Jianhua, Namaka, Michael, Zhang, Jianxiang, Deng, Youcai, Li, Xiaohui
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957145/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957145/

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