AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity

AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity

Fibrosis is emerging as a hallmark of metabolically dysregulated white adipose tissue (WAT) in obesity. Although adipose tissue fibrosis impairs adipocyte plasticity, little is known about how aberrant extracellular matrix (ECM) remodeling of WAT is initiated during the development of obesity. Here...

Full description

Bibliographic Details
Main Authors: Luo, Ting, Nocon, Allison, Fry, Jessica, Sherban, Alex, Rui, Xianliang, Jiang, Bingbing, Xu, X. Julia, Han, Jingyan, Yan, Yun, Yang, Qin, Li, Qifu, Zang, Mengwei
Format: Online
Language:English
Published: American Diabetes Association 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955985/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955985/

Similar Items