Metformin Ameliorates Hepatic Steatosis and Inflammation without Altering Adipose Phenotype in Diet-Induced Obesity

Non-alcoholic fatty liver disease (NAFLD) is closely associated with obesity and insulin resistance. To better understand the pathophysiology of obesity-associated NAFLD, the present study examined the involvement of liver and adipose tissues in metformin actions on reducing hepatic steatosis and in...

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Bibliographic Details
Main Authors: Woo, Shih-Lung, Xu, Hang, Li, Honggui, Zhao, Yan, Hu, Xiang, Zhao, Jiajia, Guo, Xin, Guo, Ting, Botchlett, Rachel, Qi, Ting, Pei, Ya, Zheng, Juan, Xu, Yiming, An, Xiaofei, Chen, Lulu, Chen, Lili, Li, Qifu, Xiao, Xiaoqiu, Huo, Yuqing, Wu, Chaodong
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956460/