SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc

SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc

Several lines of evidence indicate that connective tissue growth factor (CTGF/CCN2) stimulates chondrocyte proliferation and maturation. Given the fact that SOX9 is essential for several steps of the chondrocyte differentiation pathway, we asked whether Ctgf (Ccn2) is the direct target gene of SOX9....

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Bibliographic Details
Main Authors: Oh, Chun-do, Yasuda, Hideyo, Zhao, Weiwei, Henry, Stephen P., Zhang, Zhaoping, Xue, Ming, de Crombrugghe, Benoit, Chen, Di
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951750/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951750/

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