SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.

SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.

The transcription factor SOX9 plays an essential role in determining the fate of several cell types and is a master factor in regulation of chondrocyte development. Our aim was to determine which genes in the genome of chondrocytes are either directly or indirectly controlled by SOX9. We used RNA-Se...

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Bibliographic Details
Main Authors: Chun-do Oh, Yue Lu, Shoudan Liang, Yuko Mori-Akiyama, Di Chen, Benoit de Crombrugghe, Hideyo Yasuda
Format: Article
Language:English
Published: Public Library of Science (PLoS)
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4168005?pdf=render

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http://europepmc.org/articles/PMC4168005?pdf=render

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