Identification of cooperative genes for E2A‐PBX1 to develop acute lymphoblastic leukemia
E2A‐PBX1 is a chimeric gene product detected in t(1;19)‐bearing acute lymphoblastic leukemia (ALL) with B‐cell lineage. To investigate the leukemogenic process, we generated conditional knock‐in (cKI) mice for E2A‐PBX1, in which E2A‐PBX1 is inducibly expressed under the control of the endogenous E2...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
John Wiley and Sons Inc.
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946715/ |