FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2, and A...

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Bibliographic Details
Main Authors: Zhao, Jonathan C., Fong, Ka-Wing, Jin, Hong-Jian, Yang, Yeqing A, Kim, Jung, Yu, Jindan
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940300/