Cooperativity and Equilibrium with FOXA1 Define the Androgen Receptor Transcriptional Program

The pioneering factor FOXA1 opens chromatin to facilitate androgen receptor (AR) binding to prostate-specific genes. How FOXA1 controls the AR cistrome, however, is incompletely understood. Here we show that AR directly binds chromatin through the androgen-response elements (AREs). FOXA1 is not requ...

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Bibliographic Details
Main Authors: Jin, Hong-Jian, Zhao, Jonathan C., Wu, Longtao, Kim, Jung, Yu, Jindan
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088269/