Inclusion of Strep-Tag II in design of antigen receptors for T cell immunotherapy
The tactical introduction of Strep-tag II into synthetic antigen receptors provides engineered T cells with a marker for identification and rapid purification, and a functional element for selective antibody coated microbead-driven large-scale expansion. Such receptor designs can be applied to chime...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940167/ |