Molecular design and downstream processing of turoctocog alfa (NovoEight), a B-domain truncated factor VIII molecule
Turoctocog alfa (NovoEight) is a third-generation recombinant factor VIII (rFVIII) with a truncated B-domain that is manufactured in Chinese hamster ovary cells. No human or animal-derived materials are used in the process. The aim of this study is to describe the molecular design and purification p...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Lippincott Williams And Wilkins
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935534/ |