Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq

Direct lineage reprogramming represents a remarkable conversion of cellular and transcriptome states1–3. However, the intermediates through which individual cells progress are largely undefined. Here we used single-cell RNA-seq4–7 at multiple time points to dissect direct reprogramming from mouse em...

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Bibliographic Details
Main Authors: Treutlein, Barbara, Lee, Qian Yi, Camp, J. Gray, Mall, Moritz, Koh, Winston, Shariati, Seyed Ali Mohammad, Sim, Sopheak, Neff, Norma F., Skotheim, Jan M., Wernig, Marius, Quake, Stephen R.
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928860/