Myt1 inhibition of Cyclin A/Cdk1 is essential for fusome integrity and premeiotic centriole engagement in Drosophila spermatocytes
Drosophila Myt1 is essential for male fertility. Loss of Myt1 activity causes defective fusomes and premature centriole disengagement during premeiotic G2 phase due to lack of Myt1 inhibition of Cyclin A/Cdk1. These functions are distinct from known roles for Myt1 inhibition of Cyclin B/Cdk1 used to...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927279/ |