Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information from the existing HDF screens together with new screens per...

Full description

Bibliographic Details
Main Authors: Zhu, Jian, Davoli, Teresa, Perriera, Jill M., Chin, Christopher R., Gaiha, Gaurav D., John, Sinu P., Sigiollot, Frederic D., Gao, Geng, Xu, Qikai, Qu, Hongjing, Pertel, Thomas, Sims, Jennifer S., Smith, Jennifer A., Baker, Richard E., Maranda, Louise, Ng, Aylwin, Elledge, Stephen J., Brass, Abraham L.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926641/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926641/

Similar Items