The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

Mitochondria serve as platforms for innate immunity. The mitochondrial antiviral signalling (MAVS) protein forms aggregates that elicit robust type-I interferon induction on viral infection, but persistent MAVS signalling leads to host immunopathology; it remains unknown how these signalling aggrega...

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Bibliographic Details
Main Authors: Yoo, Young-Suk, Park, Yong-Yea, Kim, Jae-Hoon, Cho, Hyeseon, Kim, Song-Hee, Lee, Ho-Soo, Kim, Tae-Hwan, Sun Kim, You, Lee, Youngsoo, Kim, Chul-Joong, Jung, Jae U, Lee, Jong-Soo, Cho, Hyeseong
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918326/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918326/

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