Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES‐62 against clinically relevant allergens

ES‐62 is a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that protects against ovalbumin (OVA)‐induced airway hyper‐responsiveness in mice by virtue of covalently attached anti‐inflammatory phosphorylcholine (PC) residues. We have recently generated a library of small mole...

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Bibliographic Details
Main Authors: Janicova, L., Rzepecka, J., Rodgers, D. T., Doonan, J., Bell, K. S., Lumb, F. E., Suckling, C. J., Harnett, M. M., Harnett, W.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913752/