Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES‐62 against clinically relevant allergens
ES‐62 is a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that protects against ovalbumin (OVA)‐induced airway hyper‐responsiveness in mice by virtue of covalently attached anti‐inflammatory phosphorylcholine (PC) residues. We have recently generated a library of small mole...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913752/ |