Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation

•Small molecule analogues (SMAs) of the immunomodulator, ES-62, have been produced.•Two SMAs protect against oxazolone-induced skin inflammation in mouse ears.•Protection is associated with reduced cellular infiltration and collagen deposition.•Protection is associated with decreased IFNγ mRNA in th...

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Bibliographic Details
Main Authors: Al-Riyami, Lamyaa, Rodgers, David T., Rzepecka, Justyna, Pineda, Miguel A., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Format: Online
Language:English
Published: Academic Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659540/