TRF2 acts as a transcriptional regulator in tumor angiogenesis
We recently showed that telomeric repeat-binding factor 2 (TRF2) regulates gene expression to promote angiogenesis. We found that TRF2 is highly expressed in tumor vessels and transcriptionally activates platelet-derived growth factor receptor β to promote endothelial cell angiogenic properties inde...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Taylor & Francis
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905305/ |