TRF2 acts as a transcriptional regulator in tumor angiogenesis

We recently showed that telomeric repeat-binding factor 2 (TRF2) regulates gene expression to promote angiogenesis. We found that TRF2 is highly expressed in tumor vessels and transcriptionally activates platelet-derived growth factor receptor β to promote endothelial cell angiogenic properties inde...

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Bibliographic Details
Main Authors: Maï, Mounir El, Wagner, Kay-Dietrich, Michiels, Jean-François, Gilson, Eric, Wagner, Nicole
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905305/