Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes

The exact functions of all paxillin family members in mechanosensing and adhesion at invadosomes are unclear. Petropoulos et al. show that redundant and specific activities of paxillin and Hic-5 can couple original adhesion and ECM degradation in invadosomes.

Bibliographic Details
Main Authors: Petropoulos, Christos, Oddou, Christiane, Emadali, Anouk, Hiriart-Bryant, Edwige, Boyault, Cyril, Faurobert, Eva, Vande Pol, Scott, Kim-Kaneyama, Joo-ri, Kraut, Alexandra, Coute, Yohann, Block, Marc, Albiges-Rizo, Corinne, Destaing, Olivier
Format: Online
Language:English
Published: The Rockefeller University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896053/