Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis

Excessive Activation of TGFβ by Spinal Instability Causes Vertebral Endplate Sclerosis

Narrowed intervertebral disc (IVD) space is a characteristic of IVD degeneration. EP sclerosis is associated with IVD, however the pathogenesis of EP hypertrophy is poorly understood. Here, we employed two spine instability mouse models to investigate temporal and spatial EP changes associated with...

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Bibliographic Details
Main Authors: Bian, Qin, Jain, Amit, Xu, Xin, Kebaish, Khaled, Crane, Janet L., Zhang, Zhendong, Wan, Mei, Ma, Lei, Riley, Lee H., Sponseller, Paul D., Guo, X. Edward, Lu, Willian Weijia, Wang, Yongjun, Cao, Xu
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891769/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891769/

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