Continuous Cyclic Mechanical Tension Increases Ank Expression in Endplate Chondrocytes Through the TGF-β1 and p38 Pathway

The normal ANK protein has a strong influence on anti-calcification. It is known that TGF-β1 is also able to induce extracellular inorganic pyrophosphate (ePPi) elaboration via the TGF-β1-induced ank gene expression and the mitogen-activated protein kinase (MAPK) signaling acts as a downstream effec...

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Bibliographic Details
Main Authors: Xu, H., Zhang, X., Wang, H., Zhang, Y., Shi, Y.
Format: Online
Language:English
Published: PAGEPress Publications, Pavia, Italy 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794359/