Dynamics of Translation of Single mRNA Molecules In Vivo

Regulation of mRNA translation, the process by which ribosomes decode mRNAs into polypeptides, is used to tune cellular protein levels. Currently, methods for observing the complete process of translation from single mRNAs in vivo are unavailable. Here, we report the long-term (>1 hr) imaging of...

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Bibliographic Details
Main Authors: Yan, Xiaowei, Hoek, Tim A., Vale, Ronald D., Tanenbaum, Marvin E.
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889334/