Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers

Drug resistance hinder most cancer chemotherapies and leads to disease recurrence and poor survival of patients. Resistance of cancer cells towards apoptosis is the major cause of these symptomatic behaviours. Here, we showed that isoquinoline alkaloids, including liensinine, isoliensinine, dauricin...

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Bibliographic Details
Main Authors: Law, Betty Yuen Kwan, Mok, Simon Wing Fai, Chan, Wai Kit, Xu, Su Wei, Wu, An Guo, Yao, Xiao Jun, Wang, Jing Rong, Liu, Liang, Wong, Vincent Kam Wai
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884978/