Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells

Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells

Emerging evidence indicates important protective roles being played by autophagy in neurodegenerative disorders through clearance of aggregate-prone or mutant proteins. In the current study, we aimed to identify autophagy inducers from Chinese medicinal herbs as a potential neuroprotective agent tha...

Full description

Bibliographic Details
Main Authors: Wu, An-Guo, Wong, Vincent Kam-Wai, Xu, Su-Wei, Chan, Wai-Kit, Ng, Choi-In, Liu, Liang, Law, Betty Yuen-Kwan
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856081/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856081/

Similar Items