The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation*

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation*

Parasitic nematodes manufacture various carbohydrate-linked phosphorylcholine (PCh)-containing molecules, including ES-62, a protein with an N-linked glycan terminally substituted with PCh. The PCh component is biologically important because it is required for immunomodulatory effects. We showed tha...

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Bibliographic Details
Main Authors: Ahmed, Umul Kulthum, Maller, N. Claire, Iqbal, Asif J., Al-Riyami, Lamyaa, Harnett, William, Raynes, John G.
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882459/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882459/

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