The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation*
Parasitic nematodes manufacture various carbohydrate-linked phosphorylcholine (PCh)-containing molecules, including ES-62, a protein with an N-linked glycan terminally substituted with PCh. The PCh component is biologically important because it is required for immunomodulatory effects. We showed tha...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882459/ |