Prodrug Strategies for Paclitaxel

Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule...

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Bibliographic Details
Main Authors: Meng, Ziyuan, Lv, Quanxia, Lu, Jun, Yao, Houzong, Lv, Xiaoqing, Jiang, Feng, Lu, Aiping, Zhang, Ge
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881612/