A Mini-Review for Cancer Immunotherapy: Molecular Understanding of PD-1/PD-L1 Pathway & Translational Blockade of Immune Checkpoints
Interference of the binding of programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) has become a new inspiring immunotherapy for resisting cancers. To date, the FDA has approved two PD-1 monoclonal antibody drugs against cancer as well as a monoclonal antibody for PD-L1. More...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964524/ |