Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's disease
•A pipeline is presented to address HD-related confounds in diffusion MRI data.•CSF contamination affected the sensitivity to detect white matter alterations in HD.•The choice of tracking algorithm affected the reconstruction of the corpus callosum.•Tissue volume fraction is a complementary metric t...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier/North-Holland Biomedical Press
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863525/ |