Longitudinal in vivo MRI in a Huntington’s disease mouse model: global atrophy in the absence of white matter microstructural damage
Huntington’s disease (HD) is a genetically-determined neurodegenerative disease. Characterising neuropathology in mouse models of HD is commonly restricted to cross-sectional ex vivo analyses, beset by tissue fixation issues. In vivo longitudinal magnetic resonance imaging (MRI) allows for disease p...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016
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| Online Access: | http://eprints.nottingham.ac.uk/38799/ http://eprints.nottingham.ac.uk/38799/ http://eprints.nottingham.ac.uk/38799/ http://eprints.nottingham.ac.uk/38799/1/Steventon%20et%20al%202016.pdf |