Progress towards an optimal specimen support for electron cryomicroscopy

•Physical principles of electron scattering govern the design of specimen supports.•Radiation-induced motion causes loss of resolution in electron micrographs.•Specimen supports can now be designed to reduce specimen motion.•Tailored surfaces in the support allow control of particle distribution and...

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Bibliographic Details
Main Authors: Russo, Christopher J, Passmore, Lori A
Format: Online
Language:English
Published: Elsevier Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863039/