Structural characterization of the virulence factor Sda1 nuclease from Streptococcus pyogenes
Infection by Group A Streptococcus pyogenes (GAS) is a leading cause of severe invasive disease in humans, including streptococcal toxic shock syndrome and necrotizing fasciitis. GAS infections lead to nearly 163,000 annual deaths worldwide. Hypervirulent strains of S. pyogenes have evolved a pletho...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856990/ |