Inactivation of the Rgg2 Transcriptional Regulator Ablates the Virulence of Streptococcus pyogenes

Streptococcus pyogenes adapts to different niches encountered in the human host via the activity of numerous regulatory proteins including the Rgg family of transcriptional regulators. The S. pyogenes chromosome encodes four Rgg paralogues designated Rgg1 (RopB), Rgg2 (MutR), Rgg3, and Rgg4 (ComR)....

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Bibliographic Details
Main Authors: Zutkis, Anastasia A., Anbalagan, Srivishnupriya, Chaussee, Michael S., Dmitriev, Alexander V.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259489/