Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study
•A strong synergism was identified between propranolol and vinblastine in an in vitro model of angiosarcoma.•Adrenergic receptor expression was detected in angiosarcoma tumors providing a molecular target for propranolol.•Propranolol and vinblastine-based metronomic chemotherapy led to 100% response...
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Bibliographic Details
| Main Authors: |
Pasquier, Eddy,
André, Nicolas,
Street, Janine,
Chougule, Anuradha,
Rekhi, Bharat,
Ghosh, Jaya,
Philip, Deepa S.J.,
Meurer, Marie,
MacKenzie, Karen L.,
Kavallaris, Maria,
Banavali, Shripad D. |
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| Format: | Online
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| Language: | English |
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| Published: |
Elsevier
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856748/
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