Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study

Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study

•A strong synergism was identified between propranolol and vinblastine in an in vitro model of angiosarcoma.•Adrenergic receptor expression was detected in angiosarcoma tumors providing a molecular target for propranolol.•Propranolol and vinblastine-based metronomic chemotherapy led to 100% response...

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Bibliographic Details
Main Authors: Pasquier, Eddy, André, Nicolas, Street, Janine, Chougule, Anuradha, Rekhi, Bharat, Ghosh, Jaya, Philip, Deepa S.J., Meurer, Marie, MacKenzie, Karen L., Kavallaris, Maria, Banavali, Shripad D.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856748/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856748/

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