Voltage gated sodium channels as drug discovery targets

Voltage-gated sodium (NaV) channels are a family of transmembrane ion channel proteins. They function by forming a gated, water-filled pore to help establish and control cell membrane potential via control of the flow of ions between the intracellular and the extracellular environments. Blockade of...

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Bibliographic Details
Main Authors: Bagal, Sharan K, Marron, Brian E, Owen, Robert M, Storer, R Ian, Swain, Nigel A
Format: Online
Language:English
Published: Taylor & Francis Group, LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850042/