Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo

Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) encodes miRNAs from intragenomic Pol III promoters. The BLV miRNAs are abundant...

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Bibliographic Details
Main Authors: Gillet, Nicolas A., Hamaidia, Malik, de Brogniez, Alix, Gutiérrez, Gerónimo, Renotte, Nathalie, Reichert, Michal, Trono, Karina, Willems, Luc
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849745/